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Exploring the prognostic significance of set-domain containing 2 (setd2) expression in advanced and castrate-resistant prostate cancer
Gamallat, Yaser; Felipe Lima, Joema; Seyedi, Sima; Li, Qiaowang; Rokne, Jon George; Alhajj, Reda; Ghosh, Sunita; Bismar, Tarek A. (2024)SET-domain containing 2 (SETD2) is a histone methyltransferase and an epigenetic modifier with oncogenic functionality. In the current study, we investigated the potential prognostic role of SETD2 in prostate cancer. A ... -
Genomic biomarker discovery in disease progression and therapy response in bladder cancer utilizing machine learning
Liosis, Konstantinos Christos; Marouf, Ahmed Al; Rokne, Jon G.; Ghosh, Sunita; Bismar, Tarek A.; Alhajj, Reda (Multidisciplinary Digital Publishing Institute (MDPI), 2023)Cancer in all its forms of expression is a major cause of death. To identify the genomic reason behind cancer, discovery of biomarkers is needed. In this paper, genomic data of bladder cancer are examined for the purpose ... -
Serrate RNA effector molecule (SRRT) is associated with prostate cancer progression and is a predictor of poor prognosis in lethal prostate cancer
Gamallat, Yaser; Choudhry, Muhammad; Li, Qiaowang; Rokne, Jon George; Alhajj, Reda; Abdelsalam, Ramy; Ghosh, Sunita; Arbet, Jaron; Boutros, Paul C.; Bismar, Tarek A. (MDPI, 2023)Arsenite-resistance protein 2, also known as serrate RNA effector molecule (ARS2/SRRT), is known to be involved in cellular proliferation and tumorigenicity. However, its role in prostate cancer (PCa) has not yet been ...